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Sample Set Information

ID TSE1332
Title Metabolome Analysis of Oryza sativa (Rice) Using Liquid ChromatographyMass Spectrometry for Characterizing Organ Specificity of Flavonoids with Anti-inflammatory and Anti-oxidant Activity
Description Oryza sativa L. (rice) is an important staple crop across the world. In the previous study, we identified 36 specialized (secondary) metabolites including 28 flavonoids. In the present study, a metabolome analysis using liquid chromatography-mass spectrometry was conducted on the leaf, bran, and brown and polished rice grains to better understand the distribution of these metabolites. Principal component analysis using the metabolome data clearly characterized the accumulation patterns of the metabolites. Flavonoids, e.g., tricin, tricin 7-O-rutinoside, and tricin 7-O-β-D-glucopyranoside, were mainly present in the leaf and bran but not in the polished grain. In addition, anti-inflammatory and anti-oxidant activity of the metabolites were assayed in vitro. Tricin 4'-O-(erythro-β-guaiacylglyceryl)ether and isoscoparin 2''-O-(6'''-(E)-feruloyl)-glucopyranoside showed the strongest activity for inhibiting nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging, respectively.
Authors Yang, Z., Nakabayashi, R., Mori, T., Takamatsu, S., Kitanaka, S. and Saito, K.
Reference Chem. Pharm. Bull. Volume 64 (2016) Issue 7 Pages 952-956

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Data Analysis Details Information

Title Data Analysis
Description Data acquisition and processing were performed using the MassLynx 4.1 and Progenesis CoMet (Nonlinear Dynamics, Durham, NC, U.S.A.) software. Heat map visualization was performed using MeV (

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